Endocrine Abstracts

Objectives: Broad insight into metabolic disturbances caused by diabetes ketoacidosis (DKA) and persist after pH normalization.Methods: Three groups of children with type 1 diabetes were recruited: after an episode of DKA (DKA, n=20), with established diabetes (EDM, n=10) and with new onset diabetes without DKA (NDM, n=10). EDM and NDM groups were matched to the DKA one for sex and age. Serum samples were collected at three tim...

Introduction: The prevalence of obesity in elderly population increased. Obesity leads to increased morbidity and mortality as well as worsens quality of life in older individuals. Body-mass index (BMI) is the most widely used adiposity index. BMI correlates with body fatness but this index does not account for fat mass versus fat-free mass. Recently a new index of body adiposity the body adiposity index (BAI) was introduced. This novel index correlates well (in comparison to ...

Introduction: Anthropometric parameters are easy and quickly methods of assess risks of many diseases.Aim: The purpose of this study was to assess the correlation between calf circumference index, selected anthropometric (such as BMI, BAI, WHR, WHtR index) and biochemical parameters (such as concentration of 25(OH)D3, lipid profile, fasting glucose) among patients over 60 years.Materials and methods: Cross-sectional study was done ...

Introduction: Hormonal changes during menstrual cycle among women without hormonal contraception could probably influence the food intake. Sex hormones modulate body energy expenditure by affecting hypothalamus neurohormones.Aim: The aim of the study was to assess the way of nutrition among menstruating women without hormonal contraception, depend of menstrual cycle.Materials and methods: 77 menstruating women in age 19–26 ent...

Introduction: Sex hormones, such as estrogens or progesterone may have, both directly and indirectly, an influence on the appetite changes in. In addition, exogenous sex hormones are commonly used as one method of contraception.Aim: The purpose of this study was to assess whether the eating style in a group of menstruating women, taking oral hormonal contraceptives, is different in the individual menstrual cycle phases.Material and...

Introduction: Vitamin D is important for proper functioning of all body tissues. Receptors for vitamin D are also presence in thyroid gland. It’s open questions how this vitamin could modulate the thyroid function.Aim: The aim of the study was assess the concentrations of vitamin D as well as antiTPO level among patients with thyroid dysfunction hospitalised on Endocrinology Department.Materials and methods: The study was cond...

Genetic instability, i.e. loss of heterozygosity (LOH) and microsatellite instability (MSI) represent molecular disorders acquired by the cell during neoplastic transformation. Genetic instability is a frequent molecular event in thyroid pathogenesis, found at the early and the late stages of thyroid tumorigenesis. In thyroid neoplasms genetic instability was found in many chromosomal regions and is observed especially in cell-derived thyroid tumours. Alterations in PTEN loci ...

Introduction: The autoimmune process is currently the most common cause ofthe primary adrenal insufficiency cases in developed countries. The complexity of this process consists of genetic, immunological and environmental factors. It has been proven that vitamin D (VD) inhibits the production of inflammatory cytokines and can modulate immune-regulatory mechanisms.Purpose: The aim of our study was to evaluate the prevalence of VD insufficiencyin...

Introduction: Primary adrenocortical carcinoma (ACC) is a highly malignant but rare neoplasm. It can occur as a hormonally active or an inactive tumor. It is considered that about three-fourths of ACC cases are hormonally active, although they do not always give clinical symptoms. Mitotane (Lysodren) is registered by the FDA for the therapy of ACC, either for monotherapy or as a combined chemotherapy.Case report: A 34-year-old woman, with a histopatholog...

Adropin, hormone playing an important role in carbohydrates and lipids metabolism, improves mainly the glucose homeostasis. It could also play a protective role in pathogenesis and development of cardiovascular diseases. The purpose of the study was to assess the adropin concentration and some parameters of nutritional status (BMI, WHtR, BAI, VAI) as well as biochemical parameters (fasting glucose and insulin, and lipid profile). 25 patients (84% of group was women, n...